NURS 6501N Concepts of Neurological and Musculoskeletal Disorders Case Study Analysis Example

NURS 6501N Week 8: Concepts of Neurological and Musculoskeletal Disorders Case Study Analysis AssignmentNURS 6501N Week 8: Concepts of Neurological and Musculoskeletal Disorders Case Study Analysis Assignment

NURS 6501N Concepts of Neurological and Musculoskeletal Disorders Case Study Analysis Assignment Brief

Course: NURS 6501N – Advanced Pathophysiology

Assignment Title: NURS 6501N Week 8: Concepts of Neurological and Musculoskeletal Disorders Case Study Analysis Assignment

Assignment Instructions Overview

This assignment focuses on analyzing a case study related to neurological and musculoskeletal disorders, exploring their pathophysiologic processes and the impact of racial/ethnic variables on physiological functioning. Students will investigate how these systems interact to affect patient health.

Understanding Assignment Objectives

Students are tasked with:

  • Analyzing pathophysiologic processes related to neurological and musculoskeletal disorders.
  • Identifying racial/ethnic variables that may influence physiological functioning.
  • Evaluating the interaction between neurological and musculoskeletal processes in impacting patient health.

The Student’s Role

As a student, your role is to critically analyze the presented case study, applying knowledge of neurological and musculoskeletal disorders acquired through course readings and media resources. You will demonstrate understanding of disease mechanisms and their implications for patient care.

Competencies Measured

This assignment assesses competencies in:

  • Analytical thinking: Ability to dissect complex symptoms and relate them to underlying disease processes.
  • Cultural competence: Understanding the role of racial and ethnic factors in disease manifestation and management.
  • Communication: Effectively conveying diagnostic considerations and treatment implications based on identified pathophysiological mechanisms.

You Can Also Check Other Related Assessments for the NURS 6501N – Advanced Pathophysiology Course:

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NURS 6501N Week 2 Altered Physiology Assignment: Case Study Analysis Example

NURS 6501N Week 4 Case Study Analysis Assignment Example

NURS 6501N Week 5: Knowledge Check Gastrointestinal and Hepatobiliary Disorders Assignment Example

NURS 6501 Week 10 Assignment – Case study, STDs and Infertility Assignment Example

NURS 6501N Concepts of Neurological and Musculoskeletal Disorders Case Study Analysis Example

NURS 6501N Week 8 Case Study Analysis Assignment: Neurological and Musculoskeletal Disorders


This case study analysis explores the neurological and musculoskeletal pathophysiologic processes in a 67-year-old man diagnosed with Parkinson’s Disease (PD). It examines the racial and ethnic variables that may impact physiological functioning and how these processes interact to affect the patient.

Neurological and Musculoskeletal Pathophysiologic Processes

Parkinson’s Disease is a progressive neurodegenerative disorder characterized by the loss of dopamine-producing neurons in the substantia nigra region of the brain. Dopamine is essential for smooth, coordinated muscle movements. As dopamine levels decline, patients experience tremors, rigidity, bradykinesia (slowness of movement), and postural instability (DeMaagd & Philip, 2015).

In the presented case, the patient’s symptoms, such as tremors in the arms and legs, “pill-rolling” movement, rigidity, and shuffling gait, are classic manifestations of PD. The mask-like facial expression and cogwheel rigidity observed during the physical exam further support this diagnosis. The musculoskeletal symptoms stem from the neurological deficits, leading to muscle stiffness and difficulty in initiating movements (DeMaagd & Philip, 2015).

Racial and Ethnic Variables Impacting Physiological Functioning

The prevalence and progression of Parkinson’s Disease can vary among different racial and ethnic groups due to genetic, environmental, and socio-cultural factors. Research indicates that African Americans and Asians have a lower prevalence of PD compared to Caucasians. This discrepancy may be attributed to genetic variations, differences in environmental exposures, and potential disparities in access to healthcare and diagnostic services (Sauerbier et al., 2018; Dahodwala et al., 2009).

Socio-cultural factors can influence the patient’s awareness and understanding of PD, potentially delaying diagnosis and treatment. Additionally, dietary habits, levels of physical activity, and exposure to neurotoxins can vary between ethnic groups, potentially impacting disease onset and progression (Sauerbier et al., 2018).

Interaction of Processes to Affect the Patient

The neurological and musculoskeletal processes in Parkinson’s Disease are interrelated. The degeneration of dopamine-producing neurons leads to motor symptoms, such as tremors, rigidity, and bradykinesia. These motor deficits result in secondary musculoskeletal complications, including muscle stiffness, joint pain, and postural abnormalities (DeMaagd & Philip, 2015).

Racial and ethnic factors can exacerbate these issues by influencing the patient’s overall health, access to healthcare, and lifestyle. For example, if the patient belongs to an ethnic group with limited access to healthcare resources, he may experience delays in diagnosis and treatment, worsening his symptoms. Additionally, socio-cultural differences in diet and physical activity can impact the severity of musculoskeletal symptoms and overall disease progression (Sauerbier et al., 2018).


Parkinson’s Disease involves complex interactions between neurological and musculoskeletal systems, significantly impacting patients’ quality of life. Racial and ethnic variables can influence disease prevalence, progression, and patient outcomes. Understanding these factors is crucial for providing comprehensive care and developing effective treatment plans for individuals with Parkinson’s Disease.


Dahodwala, N., Siderowf, A., Xie, M., Noll, E., Stern, M., & Mandell, D. (2009). Racial differences in the diagnosis of Parkinson’s disease. Movement Disorders, 24(8), 1200-1205.

DeMaagd, G., & Philip, A. (2015). Parkinson’s disease and Its Management: Part 1: Disease Entity, Risk Factors, Pathophysiology, Clinical Presentation, and Diagnosis. Pharmacy and Therapeutics, 40(8), 504-532. Retrieved from

Sauerbier, A., Aris, A., Lim, E., Bhattacharya, K., & Chaudhuri, K. (2018). Impact of ethnicity on the natural history of Parkinson disease. Medical Journal of Australia, 208(9), 410-414. Retrieved from

Detailed Assessment Instructions for the NURS 6501N Concepts of Neurological and Musculoskeletal Disorders Case Study Analysis Assignment

Week 8: Concepts of Neurological and Musculoskeletal Disorders – Part 2

As homeowners know all too well, there is a continuous need for maintenance and repair. Some efforts are precautionary in nature, while others are the result of issues that surface over time.

Similarly, musculoskeletal disorders can develop over time. For some disorders, such as osteoporosis, precautionary treatments are a potential option. But much like issues that surface in a home over time, many musculoskeletal issues can be very serious concerns, and they can have a significant impact on patients’ lives.

This week, you continue to examine fundamental concepts of neurological and musculoskeletal disorders. You explore common disorders that impact these systems and you apply the key terms and concepts that help communicate the pathophysiological nature of these issues to patients.

Learning Objectives

Students will:

  • Analyze processes related to neurological and musculoskeletal disorders
  • Identify racial/ethnic variables that may impact physiological functioning
  • Evaluate the impact of patient characteristics on disorders and altered physiology

Learning Resources

Note: The below resources were first presented in Week 7. If you have previously reviewed them, you are encouraged to read or view them again here.

Required Readings

McCance, K. L. & Huether, S. E. (2019). Pathophysiology: The biologic basis for disease in adults and children (8th ed.). St. Louis, MO: Mosby/Elsevier.

  • Chapter 15: Structure and Function of the Cardiovascular and Lymphatic Systems (stop at Aging and the nervous system)
  • Chapter 16: Pain, Temperature Regulation, Sleep, and Sensory Function (stop at Sleep); Summary Review
  • o   Chapter 17: Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function; pp. 504–511, pp. 516–530 (start at Acute confusional states and delirium) (stop at Alterations in neuromotor functions); (Parkinson’s Disease); Summary Review
  • Chapter 18: Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction (stop at Degenerative disorders of the spine); (start at Cerebrovascular disorders) (stop at Tumors of the central nervous system); Summary Review
  • Chapter 44: Structure and Function of the Musculoskeletal System (stop at Components of muscle function); Summary Review
  • Chapter 45: Alterations of Musculoskeletal Function (stop at Bone tumors); (start at Disorders of joints); Summary Review

Chin, L. S. (2018). Spinal cord injuries. Retrieved from

Required Media

Khan Academy. (2019b). Ischemic stroke. Retrieved from ttps://

Note: The approximate length of the media program is 8 minutes. (2019, June 12). Osteoporosis – causes, symptoms, diagnosis, treatment, pathology [Video file]. Retrieved from

Note: The approximate length of the media program is 9 minutes.

Online Media from Pathophysiology: The Biologic Basis for Disease in Adults and Children

In addition to this week’s media, it is highly recommended that you access and view the resources included with the course text, Pathophysiology: The Biologic Basis for Disease in Adults and Children. Focus on the videos and animations in Chapters 15, 16, 18, and the sections of Chapters 44 and 45 that relate to the neurological and musculoskeletal systems. Refer to the Learning Resources in Week 1 for registration instructions. If you have already registered, you may access the resources at

Module 5 Assignment: Case Study Analysis

An understanding of the neurological and musculoskeletal systems is a critically important component of disease and disorder diagnosis and treatment. This importance is magnified by the impact that that these two systems can have on each other. A variety of factors and circumstances affecting the emergence and severity of issues in one system can also have a role in the performance of the other.

Effective analysis often requires an understanding that goes beyond these systems and their mutual impact. For example, patient characteristics such as, racial and ethnic variables can play a role.

An understanding of the symptoms of alterations in neurological and musculoskeletal systems is a critical step in diagnosis and treatment. For APRNs this understanding can also help educate patients and guide them through their treatment plans.

In this Assignment, you examine a case study and analyze the symptoms presented. You identify the elements that may be factors in the diagnosis, and you explain the implications to patient health.

To prepare:

By Day 1 of this week, you will be assigned to a specific case study scenario for this Case Study Assignment. Please see the “Course Announcements” section of the classroom for your assignment from your Instructor.

Assignment (1- to 2-page case study analysis)

In your Case Study Analysis related to the scenario provided, explain the following:

  • Both the neurological and musculoskeletal pathophysiologic processes that would account for the patient presenting these symptoms.
  • Any racial/ethnic variables that may impact physiological functioning.
  • How these processes interact to affect the patient.

Week 8 Case Study:

A 67-year-old man presents to the HCP with a chief complaint of tremors in his arms. He also has noticed some tremors in his leg as well. The patient is accompanied by his son, who says that his father has become “stiff” and it takes him much longer to perform simple tasks. The son also relates that his father needs help rising from his chair. Physical exam demonstrates tremors in the hands at rest and fingers exhibit “pill-rolling” movement. The patient’s face is not mobile and exhibits a mask-like appearance. His gait is uneven, and he shuffles when he walks and his head/neck, hips, and knees are flexed forward. He exhibits jerky or cogwheeling movement. The patient states that he has episodes of extreme sweating and flushing not associated with the activity. Laboratory data unremarkable and the HCP has diagnosed the patient with Parkinson’s Disease.

In your Case Study Analysis related to the scenario provided, explain the following:

  • Both the neurological and musculoskeletal pathophysiologic processes that would account for the patient presenting these symptoms.
  • Any racial/ethnic variables that may impact physiological functioning.
  • How these processes interact to affect the patient.

Day 7 of Week 8

Submit your Case Study Analysis Assignment by Day 7 of Week 8.

Reminder: The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references. The sample paper provided at the Walden Writing Center provides an example of those required elements (available at All papers submitted must use this formatting.

Submission and Grading Information

To submit your completed Assignment for review and grading, do the following:

  • Please save your Assignment using the naming convention “M5Assgn+last name+first initial.(extension)” as the name.
  • Click the Module 5 Assignment Rubric to review the Grading Criteria for the Assignment.
  • Click the Module 5 Assignment link. You will also be able to “View Rubric” for grading criteria from this area.
  • Next, from the Attach File area, click on the Browse My Computer button. Find the document you saved as “M5Assgn+last name+first initial.(extension)” and click Open.
  • If applicable: From the Plagiarism Tools area, click the checkbox for I agree to submit my paper(s) to the Global Reference Database.
  • Click on the Submit button to complete your submission.

Grading Criteria

To access your rubric:

Module 5 Assignment Rubric

Check Your Assignment Draft for Authenticity

To check your Assignment draft for authenticity:

Submit your Module 5 Assignment draft and review the originality report.

Submit Your Assignment by Day 7 of Week 8

To participate in this Assignment:

Module 5 Assignment

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