NURS 6521 Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders Assignment Example

NURS 6521 Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders AssignmentNURS 6521 Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders Assignment

NURS 6521 Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders Assignment Brief

Course: NURS 6521 – Advanced Pharmacology

Assignment Title: NURS 6521 Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders Assignment

Assignment Instructions Overview

The assignment focuses on understanding and applying pharmacotherapy principles for gastrointestinal (GI) and hepatobiliary disorders. Students will analyze a case study to formulate a diagnosis and design a drug therapy plan based on patient symptoms, medical history, and current medications. The goal is to address the underlying cause of symptoms rather than managing them superficially.

Understanding Assignment Objectives

Students are tasked with:

  • Reviewing a provided case study to identify symptoms and pertinent medical details.
  • Formulating a diagnosis considering possible GI/hepatobiliary disorders or alternative systemic causes.
  • Developing a comprehensive drug therapy plan tailored to the patient’s specific condition and existing medications.
  • Justifying the selected drug therapy plan with evidence-based reasoning.

The Student’s Role

As a student undertaking this assignment, your role is to critically analyze clinical data, integrate pharmacotherapy knowledge, and demonstrate clinical reasoning skills. You will synthesize information from the case study to propose an effective treatment strategy that aligns with best practices in advanced nursing practice.

Competencies Measured

This assignment assesses competencies in:

  • Diagnostic reasoning: Ability to interpret symptoms and medical history to reach a logical diagnosis.
  • Pharmacotherapeutic knowledge: Application of drug therapy principles specific to GI and hepatobiliary disorders.
  • Patient-centered care: Designing a treatment plan that considers individual patient factors and preferences.
  • Evidence-based practice: Justifying treatment decisions with current research and clinical guidelines.

You Can Also Check Other Related Assessments for the NURS 6521 – Advanced Pharmacology Course:

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NURS 6521 Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders Assignment Example


Gastrointestinal (GI) and hepatobiliary disorders often present with similar symptoms, making diagnosis challenging. This paper examines a case study of a patient presenting with symptoms indicative of a GI/hepatobiliary disorder. The diagnosis, rationale, and a recommended drug therapy plan are discussed based on the patient’s medical history and current medications.

Case Study Analysis

Patient Information

  • Current Medications: Synthroid, nifedipine, prednisone
  • Symptoms: Abdominal pain, cramping, nausea, bloating, fatigue


The patient likely has acute gastroenteritis, an inflammation of the stomach and intestines usually caused by infection from bacteria, viruses, or parasites. The symptoms of vomiting, diarrhea, nausea, and abdominal pain align with this condition (Ibrahim et al., 2016). The patient’s use of prednisone, an immunosuppressant, may increase susceptibility to infections, supporting this diagnosis.

Rationale for Diagnosis

Acute gastroenteritis is characterized by sudden onset of GI symptoms. The patient’s symptoms and the immunosuppressive nature of prednisone suggest a viral or bacterial infection as the underlying cause. Synthroid (for hypothyroidism) and nifedipine (for hypertension) do not directly relate to these symptoms but may influence the overall management plan.

Differential Diagnosis

Other conditions to consider include:

  • Irritable Bowel Syndrome (IBS)
  • Peptic Ulcer Disease
  • Hepatitis
  • Gallbladder Disease

However, the acute nature and symptom profile most strongly indicate gastroenteritis.

Drug Therapy Plan


  • Ondansetron 8mg: Administered to control nausea and vomiting by blocking serotonin receptors in the brain and gut.
  • Rehydration Solutions: Oral rehydration salts (ORS) to manage dehydration caused by diarrhea and vomiting.
  • Probiotics: To restore gut flora and reduce the duration of diarrhea.
  • Continue Prednisone with Tapering Plan: Gradually reduce prednisone dosage to prevent adrenal insufficiency and flare-ups of underlying conditions.


Ondansetron is effective in preventing nausea and vomiting, reducing discomfort and preventing further dehydration (Parker et al., 2018). ORS are crucial in managing fluid and electrolyte loss, ensuring proper hydration (CDC, 2020). Probiotics can help restore the natural balance of the gut microbiota, improving recovery from gastroenteritis (Suez & Elinav, 2017). Tapering prednisone prevents adverse effects associated with sudden discontinuation, maintaining the patient’s immune response without abrupt suppression (WebMD, n.d.).


The diagnosis of acute gastroenteritis is supported by the patient’s symptoms and medical history, particularly the use of prednisone. The recommended drug therapy plan, including ondansetron, ORS, probiotics, and a tapered prednisone schedule, addresses both symptom relief and underlying health maintenance. Proper management ensures effective treatment of the acute condition while safeguarding the patient’s overall health.


Parker, S. E., Van Bennekom, C., Anderka, M., & Mitchell, A. A. (2018). Ondansetron for treatment of nausea and vomiting of pregnancy and the risk of specific birth defects. Obstetrics & Gynecology, 132(2), 385-394.

CDC. (2020). Oral Rehydration Solutions (ORS). Retrieved from treatment/rehydration.html

Suez, J., & Elinav, E. (2017). Probiotics in the next-generation sequencing era. Gut Microbes, 8(2), 133-136.

Batlle, L., Mattie, R., & Irwin, R. (2016). A medication combination for the treatment of central poststroke pain via the adjuvant use of prednisone with gabapentin: a case report. PM&R, 8(3), 278-281.

WebMD. (n.d.). Can tapering off prednisone cause a flare? Retrieved from

Detailed Assessment Instructions for the NURS 6521 Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders Assignment

Assignment: Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders

Gastrointestinal (GI) and hepatobiliary disorders affect the structure and function of the GI tract. Many of these disorders often have similar symptoms, such as abdominal pain, cramping, constipation, nausea, bloating, and fatigue. Since multiple disorders can be tied to the same symptoms, it is important for advanced practice nurses to carefully evaluate patients and prescribe a treatment that targets the cause rather than the symptom.

Once the underlying cause is identified, an appropriate drug therapy plan can be recommended based on medical history and individual patient factors. In this Assignment, you examine a case study of a patient who presents with symptoms of a possible GI/hepatobiliary disorder, and you design an appropriate drug therapy plan.

To Prepare

Review the case study assigned by your Instructor for this Assignment

Reflect on the patient’s symptoms, medical history, and drugs currently prescribed.

Think about a possible diagnosis for the patient. Consider whether the patient has a disorder related to the gastrointestinal and hepatobiliary system or whether the symptoms are the result of a disorder from another system or other factors, such as pregnancy, drugs, or a psychological disorder.

Consider an appropriate drug therapy plan based on the patient’s history, diagnosis, and drugs currently prescribed.

By Day 7 of Week 4

Write a 1-page paper that addresses the following:

  • Explain your diagnosis for the patient, including your rationale for the diagnosis.
  • Describe an appropriate drug therapy plan based on the patient’s history, diagnosis, and drugs currently prescribed.
  • Justify why you would recommend this drug therapy plan for this patient. Be specific and provide examples.

Reminder: The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references. The Sample Paper provided at the Walden Writing Center offers an example of those required elements (available at All papers submitted must use this formatting.

Submission and Grading Information

To submit your completed Assignment for review and grading, do the following:

  • Please save your Assignment using the naming convention “WK4Assgn+last name+first initial.(extension)” as the name.
  • Click the Week 4 Assignment Rubric to review the Grading Criteria for the Assignment.
  • Click the Week 4 Assignment  You will also be able to “View Rubric” for grading criteria from this area.
  • Next, from the Attach File area, click on the Browse My Computer Find the document you saved as “WK4Assgn+last name+first initial.(extension)” and click Open.
  • If applicable: From the Plagiarism Tools area, click the checkbox for I agree to submit my paper(s) to the Global Reference Database.
  • Click on the Submitbutton to complete your submission.

Submit Your Assignment by Day 7 of Week 4

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