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NURS 6501N Knowledge Check Gastrointestinal and Hepatobiliary Disorders Paper Example

NURS 6501N Week 5: Knowledge Check Gastrointestinal and Hepatobiliary Disorders AssignmentNURS 6501N Week 5: Knowledge Check Gastrointestinal and Hepatobiliary Disorders Assignment

NURS 6501N Knowledge Check Gastrointestinal and Hepatobiliary Disorders Paper Assignment Brief

Course: NURS 6501N – Advanced Pathophysiology

Assignment Title: NURS 6501N Week 5: Knowledge Check Gastrointestinal and Hepatobiliary Disorders Assignment

Assignment Instructions Overview

This assignment focuses on understanding the pathophysiology of gastrointestinal (GI) and hepatobiliary disorders. Students will explore various common disorders within these categories, analyzing their causes, symptoms, and impacts on patients. The aim is to apply key terms and concepts to communicate effectively about these conditions.

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Understanding Assignment Objectives

The primary objective is to enhance students’ comprehension of the pathophysiological processes underlying GI and hepatobiliary disorders across the lifespan. This involves examining the structure and function of relevant systems and understanding how alterations can lead to disease.

The Student’s Role

Students are expected to actively engage with the provided resources, including textbook chapters, academic articles, and multimedia content. They should critically analyze the material, apply theoretical concepts to practical scenarios, and demonstrate their knowledge through a series of essay-type questions in the Knowledge Check.

Competencies Measured

This assignment measures students’ abilities to:

  • Analyze and explain the pathophysiology of GI and hepatobiliary disorders.
  • Apply theoretical knowledge to real-world clinical situations.
  • Communicate complex medical concepts in a clear and concise manner.
  • Demonstrate a comprehensive understanding of how these disorders impact patients’ lives.

You Can Also Check Other Related Assessments for the NURS 6501N – Advanced Pathophysiology Course:

NURS 6501N Week 1 Discussion: Alterations in Cellular Processes Assignment Example

NURS 6501N Week 2 Altered Physiology Assignment: Case Study Analysis Example

NURS 6501N Week 4 Case Study Analysis Assignment Example

NURS 6501N Week 8: Concepts of Neurological and Musculoskeletal Disorders Case Study Analysis Assignment Example

NURS 6501 Week 10 Assignment – Case study, STDs and Infertility Assignment Example

NURS 6501N Knowledge Check Gastrointestinal and Hepatobiliary Disorders Paper Example

Scenario 1: Peptic Ulcer Disease

Question 1:

The patient has been using ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), which is a significant cause of peptic ulcers. Additionally, smoking tobacco, consuming excessive caffeine, drinking alcohol, and psychological stress are contributing factors.

Question 2:

Ibuprofen contributes to peptic ulcer development by inhibiting the stomach’s ability to protect itself from gastric acid, reducing prostaglandin production, which normally protects the stomach lining. Smoking damages the gastroduodenal mucosa, increasing the risk of PUD. Ethanol in alcohol irritates the gastric lining, and caffeine increases acid production, all contributing to ulcer formation (Lanas & Chan, 2019).

Scenario 2: Gastroesophageal Reflux Disease (GERD)

GERD is caused by frequent acid reflux, where stomach acids backwash into the esophagus, causing burning pain. Smoking exacerbates this by relaxing the lower esophageal sphincter, while alcohol and coffee increase acid production. Obesity and connective tissue disorders are additional risk factors (Clarrett & Hachem, 2018).

Scenario 3: Upper GI Bleed

Upper GI bleeding occurs in the esophagus, stomach, or the beginning of the small intestine. It ranges from life-threatening to minor, detectable by stool tests. Common causes include peptic ulcers, esophageal varices (common in liver disease patients), and esophagitis (Steele, 2020).

Scenario 4: Diverticulitis

Diverticulitis results from the pressure build-up in the colon due to insufficient fiber in the diet, leading to constipation. Repeated pressure and straining cause diverticulosis, where small pouches (diverticula) form in the colon. These pouches can become inflamed or infected, resulting in diverticulitis (Young-Fadok, 2018).

Scenario 5: Portal Hypertension

Portal hypertension, often associated with cirrhosis from excessive alcohol consumption, occurs when blood flow through the liver is obstructed, causing increased pressure in the portal vein. This leads to complications like varices and ascites (Arab, Barrera & Arrese, 2017).

Part 2: Ascites

Ascites, the accumulation of fluid in the peritoneal cavity, is caused by portal hypertension. High pressure in the portal veins leads to leakage of protein-rich fluid from the liver and intestines into the abdomen (Arab, Barrera & Arrese, 2017).

Scenario 6: Hepatic Encephalopathy (HE)

Hepatic encephalopathy is a decline in brain function due to severe liver disease. Cirrhosis impairs the liver’s ability to remove toxins from the blood, leading to their accumulation in the brain, causing confusion, disorientation, and flapping tremors (Ferenci, 2017).

Scenario 7: Sudden Onset of Abdominal Pain

Sudden abdominal pain may indicate gastrointestinal ulcers, which can cause internal bleeding, affecting blood pressure and heart function. Untreated ulcers can lead to severe complications like heart attacks (Steele, 2020).

Scenario 8: Acute Cholecystitis

Question 1:

Gallstones are hard deposits of bile that form in the gallbladder due to excessive cholesterol, bilirubin, or inadequate bile salts. These stones can block the bile ducts, causing the gallbladder to enlarge and bile ducts to dilate (Ibrahim et al., 2018).

Question 2:

Jaundice occurs when excess bilirubin accumulates in the body due to the liver’s inability to filter it from the blood, often because of blocked bile ducts or liver dysfunction, leading to yellowing of the skin and eyes.

Scenario 9: Pancreatitis

Pancreatitis develops when digestive enzymes activate within the pancreas, causing inflammation. Chronic alcohol consumption is a major risk factor, as ethanol metabolism produces harmful byproducts that damage pancreatic cells, leading to chronic inflammation (Kleeff et al., 2017).

Scenario 10: Hepatitis B

Symptoms of Hepatitis B, such as nausea, vomiting, abdominal pain, and dark urine, along with a history of risky behaviors like unprotected sex and needle sharing, indicate a Hepatitis B infection (Terrault et al., 2018).

Scenario 11: Ulcerative Colitis (UC)

Ulcerative colitis is an immune-mediated condition where the body’s immune system attacks the cells of the digestive tract, causing inflammation and ulcers in the colon and rectum (Xu et al., 2019).

Scenario 12: Acute Kidney Injury

The patient is suffering from postrenal acute kidney injury due to nephropathy obstruction, leading to restricted urine flow. This type of AKI is associated with symptoms like lower extremity swelling and can result from congenital defects or other blockages (Mehran, Dangas & Weisbrod, 2019).

Scenario 13: Glomerular Filtration Rate (GFR)

The APRN should explain the components of GFR, which estimates blood flow through the glomeruli. Understanding normal GFR and factors affecting it helps in diagnosing renal function disorders (Bersie et al., 2020).

Scenario 14: Autoregulation

Autoregulation involves the body’s ability to maintain stable blood flow despite changes in blood pressure. The APRN should explain the relationship between blood flow, pressure, and how the body adjusts to maintain homeostasis (Wang, Ortega-Gutierrez & Peterson, 2018).

Scenario 15: Hormonal Regulation

The APRN should discuss hormonal regulation, focusing on the feedback mechanisms and the role of the thyroid system in maintaining homeostasis. Understanding how organs produce and regulate hormones is crucial (Bersie et al., 2020).

Scenario 16: Pyelonephritis

Pyelonephritis is kidney inflammation due to bacterial infection, often caused by urinary tract obstruction, which allows bacteria to multiply and spread to the kidneys (Johnson & Russo, 2018).

Scenario 17: Chronic Renal Failure

Chronic renal failure is primarily caused by diabetes and hypertension. High blood sugar and pressure damage kidney blood vessels, impairing function and leading to kidney failure over time (Mehran, Dangas & Weisbrod, 2019).

References

Arab, J. P., Barrera, F., & Arrese, M. (2017). Bile acids and portal hypertension. Annals of Hepatology, 16, S83-S86.

Bersie Larson, L. M., Gyoneva, L., Goodman, D. J., Dorfman, K. D., Segal, Y., & Barocas, V. H. (2020). Glomerular filtration and podocyte tensional homeostasis: Importance of the minor type IV collagen network. Biomechanics and Modeling in Mechanobiology.

Clarrett, D. M., & Hachem, C. (2018). Gastroesophageal Reflux Disease (GERD). Missouri Medicine, 115(3), 214.

Ferenci, P. (2017). Hepatic encephalopathy. Gastroenterology Report, 5(2), 138-147.

Ibrahim, M., Sarvepalli, S., Morris-Stiff, G., Rizk, M., Bhatt, A., Walsh, R. M., … & Burke, C. A. (2018). Gallstones: Watch and wait or intervene. Cleveland Clinic Journal of Medicine, 85(4), 323-331.

Johnson, J. R., & Russo, T. A. (2018). Acute pyelonephritis in adults. New England Journal of Medicine, 378(1), 48-59.

Kleeff, J., Whitcomb, D. C., Shimosegawa, T., Esposito, I., Lerch, M. M., Gress, T., … & Muñoz, J. E. D. (2017). Chronic pancreatitis. Nature Reviews Disease Primers, 3(1), 1-18.

Lanas, A., & Chan, F. K. (2019). Peptic ulcer disease. The Lancet, 390(10094), 613-624.

Mehran, R., Dangas, G. D., & Weisbord, S. D. (2019). Contrast-associated acute kidney injury. New England Journal of Medicine, 380(22), 2146-2155.

Steele, C. (2020). Upper GI bleed. In Resources for Optimal Care of Emergency Surgery (pp. 137-137). Springer, Cham.

Terrault, N. A., Lok, A. S., McMahon, B. J., Chang, K. M., Hwang, J. P., Jonas, M. M., … & Wong, J. B. (2018). Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance. Hepatology, 67(4), 1560-1599.

Wang, A., Ortega-Gutierrez, S., & Petersen, N. H. (2018). Autoregulation in the Neuro ICU. Current Treatment Options in Neurology, 20(6), 20.

Xu, X., Yang, W., Liang, Q., Shi, Y., Zhang, W., Wang, X., … & Yin, L. (2019). Efficient and targeted drug/siRNA co-delivery mediated by reversibly crosslinked polymersomes toward the anti-inflammatory treatment of ulcerative colitis (UC). Nano Research, 12(3), 659-667.

Young-Fadok, T. M. (2018). Diverticulitis. New England Journal of Medicine, 379(17), 1635-1642.

Detailed Assessment Instructions for the NURS 6501N Knowledge Check Gastrointestinal and Hepatobiliary Disorders Assignment

Week 5: Concepts of Gastrointestinal and Hepatobiliary Disorders

Patients of gastrointestinal and hepatobiliary disorders often face life-altering changes, including changes to diet, new treatment regimens, and more. For some disorders, treatments can include surgery.

Gastrointestinal conditions, such as ulcers, diverticulitis, and pancreatitis, often cause varying levels of pain and discomfort. Hepatobiliary conditions can also bring significant changes to patient routines and well-being.

This week, you examine fundamental concepts of gastrointestinal and hepatobiliary disorders. You explore common disorders in these categories, and you apply the key terms and concepts that help communicate the pathophysiological nature of these issues to patients.

Learning Objectives

Students will:

  • Analyze concepts and principles of pathophysiology across the life span

Learning Resources

Required Readings

McCance, K. L. & Huether, S. E. (2019). Pathophysiology: The biologic basis for disease in adults and children (8th ed.). St. Louis, MO: Mosby/Elsevier.

  • Chapter 38: Structure and Function of the Renal and Urological Systems including Summary Review
  • Chapter 39: Alteration of Renal and Urinary Function (stop at Fluids and electrolytes); Summary Review
  • Chapter 41: Structure and Function of the Digestive System (stop at Tests of digestive function); Summary Review
  • Chapter 42: Alterations of Digestive Function (stop at Cancer of the digestive track); Summary Review

Osna, N. A., Donohue, T. M., Jr., & Kharbanda, K. K. (2017). Alcoholic liver disease: Pathogenesis and current management. Alcohol Research: Current Reviews, 38(2), 7–21

Document: NURS 6501 Midterm Exam Review (PDF document)

Note: Use this document to help you as you review for your Midterm Exam in Week 6.

Required Media

Module 3 Overview with Dr. Tara Harris

Dr. Tara Harris reviews the structure of Module 3 as well as the expectations for the module. Consider how you will manage your time as you review your media and Learning Resources throughout the module to prepare for your Knowledge Check. (2m)

Liver Function Tests

MedCram. (2013, April 14). Liver function tests LFTs explained clearly by MedCram.com [Video file]. Retrieved from https://www.youtube.com/watch?v=bFdTgty0T0I

Note: The approximate length of the media program is 11 minutes.

Liver Diseases

MedCram. (2019, May 15). Diagnosis of key liver diseases: Hepatitis A, B C vs. alcoholic vs. ischemic (AST vs ALT labs) [Video file]. Retrieved from https://www.youtube.com/watch?v=ZZRHA2JvCGA

Note: The approximate length of the media program is 13 minutes.

Liver Pathophysiology

MedCram. (2013, April 9). Liver explained clearly: Pathophysiology, LFTs, hepatic diseases  [Video file]. Retrieved from https://www.youtube.com/watch?v=BTGkB8nOu7g

Note: The approximate length of the media program is 14 minutes.

Online Media from Pathophysiology: The Biologic Basis for Disease in Adults and Children

In addition to this week’s media, it is highly recommended that you access and view the resources included with the course text, Pathophysiology: The Biologic Basis for Disease in Adults and Children. Focus on the videos and animations in Chapters 41 and 42 that relate to the hepatobiliary system. Refer to the Learning Resources in Week 1 for registration instructions. If you have already registered, you may access the resources at https://evolve.elsevier.com/

Knowledge Check: Gastrointestinal and Hepatobiliary Disorders

In this exercise, you will complete a 10- to 20-essay type question Knowledge Check to gauge your understanding of this module’s content.

Possible topics covered in this Knowledge Check include:

    • Ulcers
    • Hepatitis markers
    • After HP shots
    • Gastroesophageal Reflux Disease
    • Pancreatitis
    • Liver failure—acute and chronic
    • Gall bladder disease
    • Inflammatory bowel disease
    • Diverticulitis
    • Jaundice
    • Bilirubin
    • Gastrointestinal bleed – upper and lower
    • Hepatic encephalopathy
    • Intra-abdominal infections (e.g., appendicitis)
    • Renal blood flow
    • Glomerular filtration rate
    • Kidney stones
    • Infections – urinary tract infections, pyelonephritis
    • Acute kidney injury
    • Renal failure – acute and chronic

Complete the Knowledge Check By Day 7 of Week 5

To complete this Knowledge Check:

Module 3 Knowledge Check

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NURS 6501N Cardiovascular and Respiratory Disorders Case Study Analysis Example

NURS 6501N Week 4 Case Study Analysis AssignmentNURS 6501N Week 4 Case Study Analysis Assignment

NURS 6501N Cardiovascular and Respiratory Disorders Case Study Analysis Assignment Brief

Course: NURS 6501N – Advanced Pathophysiology

Assignment Title: NURS 6501N Week 4 Case Study Analysis Assignment

Assignment Instructions Overview

This assignment focuses on the analysis of cardiovascular and respiratory disorders through a case study. The objective is to understand the pathophysiologic processes, the impact of racial/ethnic variables, and how these processes interact within the patient. This involves a detailed examination of symptoms, diagnosis, and the implications for patient health.

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Understanding Assignment Objectives

The primary objectives are to:

  • Analyze the pathophysiologic processes related to cardiovascular and respiratory disorders.
  • Examine the alterations in these systems and their resultant disease processes.
  • Understand the influence of racial and ethnic variables on physiological functioning.
  • Evaluate how patient characteristics impact disorders and altered physiology.

The Student’s Role

Students are expected to:

  • Engage in a thorough review of relevant medical literature and course materials.
  • Critically analyze a provided case study scenario.
  • Identify and explain the cardiovascular and cardiopulmonary pathophysiologic processes presented in the case.
  • Discuss any racial/ethnic variables that may influence physiological functioning.
  • Assess how these processes interact to affect the patient’s health.
  • Compile a 1-2 page case study analysis that adheres to academic standards and formatting guidelines provided by the institution.

Competencies Measured

The assignment measures several competencies, including:

  • Critical Thinking: Ability to analyze complex medical scenarios and synthesize information from various sources.
  • Clinical Knowledge: Understanding of cardiovascular and respiratory systems, disease processes, and treatment protocols.
  • Cultural Competence: Awareness of how racial and ethnic variables can impact health and disease outcomes.
  • Communication: Ability to articulate findings clearly and effectively in written form.
  • Research Skills: Proficiency in sourcing and referencing relevant academic literature.

You Can Also Check Other Related Assessments for the NURS 6501N – Advanced Pathophysiology Course:

NURS 6501N Week 1 Discussion: Alterations in Cellular Processes Assignment Example

NURS 6501N Week 2 Altered Physiology Assignment: Case Study Analysis Example

NURS 6501N Week 5: Knowledge Check Gastrointestinal and Hepatobiliary Disorders Assignment Example

NURS 6501N Week 8: Concepts of Neurological and Musculoskeletal Disorders Case Study Analysis Assignment Example

NURS 6501 Week 10 Assignment – Case study, STDs and Infertility Assignment Example

NURS 6501N Cardiovascular and Respiratory Disorders Case Study Analysis Example

NURS 6501N Week 4 Case Study Analysis Assignment: COPD Exacerbation

Introduction

This case study examines a 45-year-old woman presenting with shortness of breath, a worsening cough with thick green sputum, and fevers over three days. She has a history of Chronic Obstructive Pulmonary Disease (COPD) with a chronic cough, which has exacerbated recently, disrupting her sleep. The patient’s clinical presentation, including a flattened diaphragm, increased anterior-posterior (AP) diameter on chest X-ray (CXR), and hyper resonance with coarse rales and rhonchi on auscultation, indicates an acute exacerbation of COPD. This analysis explores the cardiovascular and respiratory pathophysiological processes underlying her symptoms, considers any racial/ethnic factors affecting her condition, and examines how these processes interact to impact her health.

Cardiovascular and Cardiopulmonary Pathophysiologic Processes

COPD is characterized by persistent respiratory symptoms and airflow limitation due to airway and/or alveolar abnormalities, typically caused by significant exposure to noxious particles or gases (McCance & Huether, 2019). The pathophysiological processes in COPD involve chronic inflammation, airway remodeling, and destruction of pulmonary structures, leading to obstructed airflow, air trapping, and hyperinflation (Inamdar & Inamdar, 2016).

In this patient, the exacerbation symptoms—shortness of breath, increased cough with thick sputum, and fever—suggest a possible bacterial infection, complicating her COPD. The thickened sputum and fever indicate an inflammatory response to infection, which exacerbates the chronic inflammatory state of COPD (McCance & Huether, 2019). The increased work of breathing due to airflow obstruction and hyperinflation leads to a flattened diaphragm and an increased AP diameter on CXR. Hyper resonance on auscultation indicates air trapping, while coarse rales and rhonchi suggest secretions in the airways.

Racial/Ethnic Variables Impacting Physiological Functioning

Racial and ethnic factors can significantly impact the presentation and progression of COPD. Studies have shown that African Americans and other minority groups often experience higher morbidity and mortality rates related to COPD compared to their white counterparts. Factors contributing to these disparities include genetic predispositions, socioeconomic status, environmental exposures, and access to healthcare (CDC, 2016).

African Americans, for example, may have a higher prevalence of certain risk factors such as smoking, urban living with greater exposure to air pollutants, and lower socioeconomic status, all of which can exacerbate COPD. Additionally, genetic factors may influence the severity and progression of the disease. These variables can lead to differences in how COPD manifests and progresses among different racial and ethnic groups (McCance & Huether, 2019).

Interaction of Processes Affecting the Patient

The interplay between the respiratory and cardiovascular systems is crucial in understanding this patient’s condition. COPD can lead to pulmonary hypertension due to chronic hypoxia and vasoconstriction in the pulmonary arteries. This increases the workload on the right side of the heart, potentially leading to right-sided heart failure, also known as cor pulmonale (McCance & Huether, 2019).

In this patient, the acute exacerbation increases the severity of hypoxia, further straining the cardiovascular system. The increased effort to breathe due to airflow limitation and hyperinflation causes significant respiratory muscle fatigue. As the respiratory muscles tire, the efficiency of ventilation decreases, leading to worsening hypercapnia (elevated CO2 levels) and hypoxemia (decreased O2 levels), which can have systemic effects, including increased cardiac workload and potential for arrhythmias (Inamdar & Inamdar, 2016).

Conclusion

This case study highlights the complex interplay between the cardiovascular and respiratory systems in a patient with an acute exacerbation of COPD. Understanding the pathophysiological processes involved in COPD, including chronic inflammation, airway remodeling, and airflow limitation, is critical for effective diagnosis and management. Racial and ethnic variables, such as socioeconomic status and environmental exposures, play a significant role in the progression and outcomes of COPD. Addressing these factors is essential for improving patient care and reducing health disparities. The interaction of these processes underscores the importance of a comprehensive approach to managing COPD, particularly during acute exacerbations.

References

Centers for Disease Control and Prevention (CDC). (2016). Chronic Obstructive Pulmonary Disease (COPD) includes: Chronic Bronchitis and Emphysema. Retrieved from http://www.cdc.gov/copd/index.html

Inamdar, A. A., & Inamdar, A. C. (2016). Heart failure: Diagnosis, management, and utilization. Journal of Clinical Medicine, 5(7), 62. doi:10.3390/jcm5070062

McCance, K. L., & Huether, S. E. (2019). Pathophysiology: The biologic basis for disease in adults and children (8th ed.). St. Louis, MO: Mosby/Elsevier.

Detailed Assessment Instructions for the NURS 6501N Cardiovascular and Respiratory Disorders Case Study Analysis Assignment

Week 4: Alterations in the Cardiovascular and Respiratory Systems

Cardiovascular and respiratory disorders can quickly become dangerous healthcare matters, and they routinely land among the leading causes of hospital admissions. Disorders in these areas are complicated by the fact that these two systems work so closely as contributors to overall health. APRNs working to form a similarly close partnership with patients must demonstrate not only support and compassion, but expertise to guide the understanding of diagnoses and treatment plans. This includes an understanding of patient medical backgrounds, relevant characteristics, and other variables that can be factors in their diagnoses and treatments.

This week, you examine alterations in the cardiovascular and respiratory systems and the resultant disease processes. You also consider patient characteristics, including racial and ethnic variables, and the impact they have on altered physiology.

Learning Objectives

Students will:

  • Analyze processes related to cardiovascular and respiratory disorders
  • Analyze alterations in the cardiovascular and respiratory systems and the resultant disease processes
  • Analyze racial/ethnic variables that may impact physiological functioning
  • Evaluate the impact of patient characteristics on disorders and altered physiology

Learning Resources

Required Readings

McCance, K. L. & Huether, S. E. (2019). Pathophysiology: The biologic basis for disease in adults and children (8th ed.). St. Louis, MO: Mosby/Elsevier.

  • Chapter 32: Structure and Function of the Cardiovascular and Lymphatic Systems; Summary Review
  • Chapter 33: Alterations of Cardiovascular Function (stop at Dysrhythmias); Summary Review
  • Chapter 35: Structure and Function of the Pulmonary System; Summary Review
  • Chapter 36: Alterations of Pulmonary Function (stop at Disorders of the chest wall and pleura); (obstructive pulmonary diseases) (stop at Pulmonary artery hypertension); Summary Review

Note: The above chapters were first presented in the Week 3 resources. If you read them previously you are encouraged to review them this week.

Inamdar, A. A. & Inamdar, A. C. (2016). Heart failure: Diagnosis, management, and utilization, 5(7). doi:10.3390/jcm5070062

Note: The above article was first presented in the Week 3 resources. If you read it previously you are encouraged to review it this week.

Required Media

Pneumonia

MedCram. (2015, September 14). Pneumonia explained clearly by MedCram [Video file]. Retrieved from https://www.youtube.com/watch?v=nqyPECmkSeo

Note: The approximate length of the media program is 13 minutes.
(Previously reviewed in Week 3)

Online Media from Pathophysiology: The Biologic Basis for Disease in Adults and Children

In addition to this week’s media, it is highly recommended that you access and view the resources included with the course text, Pathophysiology: The Biologic Basis for Disease in Adults and Children. Focus on the videos and animations in Chapters 32, 33, 35, and 36 that relate to cardiorespiratory systems and alteration in cardiorespiratory systems. Refer to the Learning Resources in Week 1 for registration instructions. If you have already registered, you may access the resources at https://evolve.elsevier.com/

Module 2 Assignment: Case Study Analysis

An understanding of the cardiovascular and respiratory systems is a critically important component of disease diagnosis and treatment. This importance is magnified by the fact that these two systems work so closely together. A variety of factors and circumstances that impact the emergence and severity of issues in one system can have a role in the performance of the other.

Effective disease analysis often requires an understanding that goes beyond these systems and their capacity to work together. The impact of patient characteristics, as well as racial and ethnic variables, can also have an important impact.

An understanding of the symptoms of alterations in cardiovascular and respiratory systems is a critical step in diagnosis and treatment of many diseases. For APRNs this understanding can also help educate patients and guide them through their treatment plans.

In this Assignment, you examine a case study and analyze the symptoms presented. You identify the elements that may be factors in the diagnosis, and you explain the implications to patient health.

Scenario 4 (week 4):

45-year-old woman presents with the chief complaint of 3-day duration of shortness of breath, cough with thick green sputum production, and fevers. The patient has a history of COPD with a chronic cough but states the cough has gotten much worse and is interfering with her sleep. Sputum is thicker and harder for her to expectorate. CXR reveals a flattened diaphragm and an increased AP diameter. Auscultation demonstrates hyper resonance and coarse rales and rhonchi throughout all lung fields.

To prepare:

By Day 1 of this week, you will be assigned to a specific case study scenario for this Case Study Assignment. Please see the “Course Announcements” section of the classroom for your assignment from your Instructor.

Assignment (1- to 2-page case study analysis)

In your Case Study Analysis related to the scenario provided, explain the following

The cardiovascular and cardiopulmonary pathophysiologic processes that result in the patient presenting these symptoms.

Any racial/ethnic variables that may impact physiological functioning.

How these processes interact to affect the patient.

By Day 7 of Week 4

Submit your Case Study Analysis Assignment by Day 7 of Week 4

Reminder: The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references. The sample paper provided at the Walden Writing Center provides an example of those required elements (available at https://academicguides.waldenu.edu/writingcenter/templates). All papers submitted must use this formatting.

In your Case Study Analysis related to the scenario provided, explain the following

  • The cardiovascular and cardiopulmonary pathophysiologic processes that result in the patient presenting these symptoms.
  • Any racial/ethnic variables that may impact physiological functioning.
  • How these processes interact to affect the patient.

By Day 7 of Week 4

Submit your Case Study Analysis Assignment by Day 7 of Week 4

Reminder: The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references. The sample paper provided at the Walden Writing Center provides an example of those required elements (available at https://academicguides.waldenu.edu/writingcenter/templates). All papers submitted must use this formatting.

Submission and Grading Information

To submit your completed Assignment for review and grading, do the following:

  • Please save your Assignment using the naming convention “M2Assgn+last name+first initial.(extension)” as the name.
  • Click the Module 2 Assignment Rubric to review the Grading Criteria for the Assignment.
  • Click the Module 2 Assignment link. You will also be able to “View Rubric” for grading criteria from this area.
  • Next, from the Attach File area, click on the Browse My Computer button. Find the document you saved as “M2Assgn+last name+first initial.(extension)” and click Open.
  • If applicable: From the Plagiarism Tools area, click the checkbox for I agree to submit my paper(s) to the Global Reference Database.
  • Click on the Submit button to complete your submission.

Grading Criteria

To access your rubric:

Module 2 Assignment Rubric

Check Your Assignment Draft for Authenticity

To check your Assignment draft for authenticity:

Submit your Module 2 Assignment draft and review the originality report.

Submit Your Assignment by Day 7 of Week 4

To participate in this Assignment:

Module 2 Assignment

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NURS 6501N Altered Physiology Case Study Analysis Example

NURS 6501N Week 2 Altered Physiology Assignment: Case Study AnalysisNURS 6501N Week 2 Altered Physiology Assignment: Case Study Analysis

NURS 6501N Altered Physiology Case Study Analysis Assignment Brief

Course: NURS 6501N – Advanced Pathophysiology

Assignment Title: NURS 6501N Week 2 Altered Physiology Assignment: Case Study Analysis

Assignment Instructions Overview

This assignment involves analyzing a case study to understand the physiological alterations within the immune system that lead to disease. Advanced Practice Registered Nurses (APRNs) must demonstrate a comprehensive understanding of disease processes, patient backgrounds, and other relevant factors to provide effective care and education to patients. You will be required to utilize the course readings and resources to support your analysis.

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Understanding Assignment Objectives

The primary objectives of this assignment are to:

  • Evaluate Cellular Processes: Examine how alterations within cellular processes contribute to disease development.
  • Analyze Immune System Alterations: Identify and describe changes in the immune system that result in specific disease processes.
  • Identify Racial/Ethnic Variables: Recognize how racial and ethnic factors may impact physiological functioning and disease progression.
  • Evaluate Patient Characteristics: Assess how individual patient characteristics affect disorders and altered physiological states.

The Student’s Role

As a student, your role is to:

  • Carefully review the assigned case study and associated symptoms.
  • Conduct a detailed analysis to explain why the patient presented with the described symptoms.
  • Identify any genetic factors that may be contributing to the disease.
  • Discuss the process of immunosuppression and its effects on body systems.
  • Utilize evidence from the course readings and additional resources to support your analysis and conclusions.

Competencies Measured

This assignment will help measure the following competencies:

  • Critical Thinking: Ability to analyze complex scenarios and understand the underlying physiological processes.
  • Application of Knowledge: Application of pathophysiological concepts to real-world case studies.
  • Research and Evidence-Based Practice: Integration of current research and evidence to support clinical reasoning and decision-making.
  • Communication: Clear and concise presentation of analysis and findings in a professional, academic format.

You Can Also Check Other Related Assessments for the NURS 6501N – Advanced Pathophysiology Course:

NURS 6501N Week 1 Discussion: Alterations in Cellular Processes Assignment Example

NURS 6501N Week 4 Case Study Analysis Assignment Example

NURS 6501N Week 5: Knowledge Check Gastrointestinal and Hepatobiliary Disorders Assignment Example

NURS 6501N Week 8: Concepts of Neurological and Musculoskeletal Disorders Case Study Analysis Assignment Example

NURS 6501 Week 10 Assignment – Case study, STDs and Infertility Assignment Example

NURS 6501N Altered Physiology Case Study Analysis Example

Week 2 Case Study Analysis: Altered Physiology

Introduction

Understanding the underlying cellular and genetic mechanisms of diseases is critical for diagnosing and managing patient conditions. This analysis will examine a patient’s symptoms, identify relevant genes associated with the disease, and explain the process and impact of immunosuppression on the body.

Symptoms and Disease Presentation

The patient presents with crampy left lower quadrant pain, which is a common symptom of diverticulitis. Diverticulitis is an inflammation or infection of the diverticula, small pouches that can form in the walls of the digestive tract. This condition is often associated with lower abdominal pain, fever, and changes in bowel habits such as constipation or diarrhea. The patient’s dietary habits, particularly a low fiber intake, contribute to the development of diverticulitis by causing harder stools and increased bowel pressure (Feuerstein & Falchuk, 2016).

Genetic Factors

Given the patient’s family history, with a grandfather who died of colon cancer, there is a significant genetic component to consider. Colon cancer can be inherited through mutations in several genes, most notably MSH6, MSH2 (both located on chromosome 2), and MLH1 (located on chromosome 3). These genes are involved in DNA mismatch repair. Mutations in these genes result in the accumulation of DNA errors, leading to the development of cancerous cells (American Cancer Society, n.d.).

Immunosuppression and Its Effects

Immunosuppression refers to the reduction of the immune system’s efficacy, which can be caused by diseases like HIV or by drugs used in conditions such as cancer or post-organ transplantation to prevent rejection (Axelrad, Lichtiger, & Yajnik, 2016). The administration of immunosuppressive drugs, such as corticosteroids, cyclosporine, and azathioprine, can profoundly impact the body’s immune response. While these drugs help in preventing the rejection of transplanted organs, they also make the body more susceptible to infections and malignancies due to the suppressed immune response (Rosenthal & Moore, 2015).

Immunosuppression can lead to several systemic effects, including:

  • Increased Infection Risk: The body becomes less capable of fighting off pathogens, leading to a higher susceptibility to infections.
  • Muscle and Bone Effects: Immunosuppressive drugs can lead to decreased muscle function and bone density, increasing the risk of fractures and osteoporosis.
  • Metabolic Changes: These drugs can alter the body’s glucose metabolism, increasing the risk of high blood sugar and secondary diabetes.
  • Cardiovascular Risks: There is an elevated risk of developing cardiovascular diseases due to the combined effects of the drugs and the body’s altered immune response (Axelrad et al., 2016; Rosenthal & Moore, 2015).

Conclusion

The patient’s symptoms are indicative of diverticulitis, exacerbated by a low-fiber diet. The genetic predisposition to colon cancer, as evidenced by the family history, highlights the importance of genetic factors in disease development. Immunosuppression, while necessary in some treatment protocols, poses significant risks to the body’s ability to fight infections and maintain overall health. Effective management of these conditions requires a thorough understanding of the underlying cellular processes and genetic influences.

References

Axelrad, J. E., Lichtiger, S., & Yajnik, V. (2016). Inflammatory bowel disease and cancer: The role of inflammation, immunosuppression, and cancer treatment. World Journal of Gastroenterology, 22(20), 4794-4801.

Feuerstein, J. D., & Falchuk, K. R. (2016). Diverticulosis and diverticulitis. Mayo Clinic Proceedings, 91(8), 1094-1104.

American Cancer Society. (n.d.). Causes of Colorectal Cancer | Is Colon Cancer Hereditary?. Retrieved from https://www.cancer.org/cancer/colon-rectal-cancer/causes-risks-prevention/what-causes.html

Lockyer, S., Spiro, A., & Stanner, S. (2016). Dietary fibre and the prevention of chronic disease–should health professionals be doing more to raise awareness?. Nutrition Bulletin, 41(3), 214-231.

Rosenthal, M. D., & Moore, F. A. (2015). Persistent inflammatory, immunosuppressed, catabolic syndrome (PICS): A new phenotype of multiple organ failure. Journal of Advanced Nutritional and Human Metabolism, 1(1).

Detailed Assessment Instructions for the NURS 6501N Altered Physiology Case Study Analysis Assignment

 Week 2: Altered Physiology

With a place squarely in the spotlight for patients diagnosed with all manner of disease, APRNs must demonstrate not only support and compassion, but expertise to guide patients’ understanding of diagnoses and treatment plans.

This expertise goes beyond an understanding of disease and sciences, such as cellular pathophysiology. APRNs must become experts in their patients, understanding their medical backgrounds, pertinent characteristics, and other variables that can be factors in their diagnoses and treatments.

This week, you examine alterations in the immune system and the resultant disease processes. You consider patient characteristics, including racial and ethnic variables, and the impact they have on altered physiology.

Learning Objectives

Students will:

  • Evaluate cellular processes and alterations within cellular processes
  • Analyze alterations in the immune system that result in disease processes
  • Identify racial/ethnic variables that may impact physiological functioning
  • Evaluate the impact of patient characteristics on disorders and altered physiology

Learning Resources

Required Readings

McCance, K. L. & Huether, S. E. (2019). Pathophysiology: The biologic basis for disease in adults and children (8th ed.). St. Louis, MO: Mosby/Elsevier.

  • Chapter 1: Cellular Biology; Summary Review
  • Chapter 2: Altered Cellular and Tissue Biology: Environmental Agents(pp. 46-61; begin again with Manifestations of Cellular Injury pp. 83-97); Summary Review
  • Chapter 3: The Cellular Environment: Fluids and Electrolytes, Acids, and Bases,
  • Chapter 4: Genes and Genetic Diseases (stop at Elements of formal genetics); Summary Review
  • Chapter 5: Genes, Environment-Lifestyle, and Common Diseases (stop at Genetics of common diseases); Summary Review
  • Chapter 7: Innate Immunity: Inflammation and Wound Healing
  • Chapter 8: Adaptive Immunity (stop at Generation of clonal diversity); Summary Review
  • Chapter 9: Alterations in Immunity and Inflammation (stop at Deficiencies in immunity); Summary Review
  • Chapter 10: Infection (stop at Infectious parasites and protozoans); (start at HIV); Summary Review
  • Chapter 11: Stress and Disease (stop at Stress, illness & coping)Summary Review
  • Chapter 12: Cancer Biology (stop at Resistance to destruction); Summary Review
  • Chapter 13: Cancer Epidemiology (stop at Environmental-Lifestyle factors); Summary Review

Note: You previously read these chapters in Week 1 and you are encouraged to review once again for this week.

Justiz-Vaillant, A. A., & Zito, P. M. (2019). Immediate hypersensitivity reactions. In StatPearls. Treasure Island, FL: StatPearls Publishing. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK513315/

Credit Line: Immediate Hypersensitivity Reactions – StatPearls – NCBI Bookshelf. (2019, June 18). Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK513315/. Used with permission of Stat Pearls.
Note: This article was presented in the Week 1 resources. If you read it previously you are encouraged to review it this week.

Required Media

Immunity and Inflammation

Khan Academy (2010, February 24). Inflammatory response | Human anatomy and physiology  | Health & medicine [Video file]. Retrieved from https://www.youtube.com/watch?v=FXSuEIMrPQk

Note: The approximate length of the media program is 14 minutes.

Soo, P. (2018, July 28). Pathophysiology Ch 10 alterations in immune function [Video file]. Retrieved from https://www.youtube.com/watch?v=Jz0wx1-jTds

Note: The approximate length of the media program is 37 minutes.

Acid-Base Balance #1

MedCram. (2012, April 28). Medical acid base balance, disorders & ABGs explained clearly [Video file]. Retrieved from https://www.youtube.com/watch?v=4wMEMhvrQxE

Note: The approximate length of the media program is 13 minutes.

Acid-Base Balance #2

MedCram. (2012, April 29). Medical acid base balance, disorders & ABGs explained clearly | 2 of 8 [Video file]. Retrieved from https://www.youtube.com/watch?v=GmEeKVTpOKI

Note: The approximate length of the media program is 15 minutes.

Hyponatremia

MedCram. (2017, December 23). Hyponatremia explained clearly [LK1] (remastered) – Electrolyte imbalances [Video file]. Retrieved from https://www.youtube.com/watch?v=bLajK5Vy55M

Note: The approximate length of the media program is 15 minutes.

Online Media from Pathophysiology: The Biologic Basis for Disease in Adults and Children

In addition to this week’s media, it is highly recommended that you access and view the resources included with the course text, Pathophysiology: The Biologic Basis for Disease in Adults and Children. Focus on the videos and animations in Chapters 3, 7, and 8 that relate to alterations in immunity, hyponatremia, and acid/base balance.

Note: To access the online resources included with the text, you need to complete the FREE online registration that is located at https://evolve.elsevier.com/cs/store?role=student

To Register to View the Content

  1. Go to https://evolve.elsevier.com/cs/store?role=student
  2. Enter the name of the textbook, Pathophysiology: The Biologic Basis for Disease in Adults and Children, or ISBN 9780323654395 (name of text without the edition number) in the Search textbox.
  3. Complete the registration process.

To View the Content for This Text

  1. Go to https://evolve.elsevier.com/
  2. Click on Student Site.
  3. Type in your username and password.
  4. Click on the Login button.
  5. Click on the plus sign icon for Resources on the left side of the screen.
  6. Click on the name of the textbook for this course.
  7. Expand the menu on the left to locate all the chapters.
  8. Navigate to the desired content (checklists, videos, animations, etc.).

Note: Clicking on the URLs in the APA citations for the Resources from the textbook will not link directly to the desired online content. Use the online menu to navigate to the desired content.

Module 1 Assignment: Case Study Analysis

An understanding of cells and cell behavior is a critically important component of disease diagnosis and treatment. But some diseases can be complex in nature, with a variety of factors and circumstances impacting their emergence and severity.

Effective disease analysis often requires an understanding that goes beyond isolated cell behavior. Genes, the environments in which cell processes operate, the impact of patient characteristics, and racial and ethnic variables all can have an important impact.

An understanding of the signals and symptoms of alterations in cellular processes is a critical step in the diagnosis and treatment of many diseases. For APRNs, this understanding can also help educate patients and guide them through their treatment plans.

In this Assignment, you examine a case study and analyze the symptoms presented. You identify cell, gene, and/or process elements that may be factors in the diagnosis, and you explain the implications to patient health.

To prepare:

By Day 1 of this week, you will be assigned to a specific case study for this Case Study Assignment. Please see the “Course Announcements” section of the classroom for your assignment from your Instructor.

The Assignment (1- to 2-page case study analysis)

Develop a 1- to 2-page case study analysis in which you:

  • Explain why you think the patient presented the symptoms described.
  • Identify the genes that may be associated with the development of the disease.
  • Explain the process of immunosuppression and the effect it has on body systems.

By Day 7 of Week 2

Submit your Case Study Analysis Assignment by Day 7 of Week 2.

Reminder: The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references. The sample paper provided at the Walden Writing Center provides an example of those required elements (available at https://academicguides.waldenu.edu/writingcenter/templates). All papers submitted must use this formatting.

Submission and Grading Information

To submit your completed Assignment for review and grading, do the following:

  • Please save your Assignment using the naming convention “M1Assgn+last name+first initial.(extension)” as the name.
  • Click the Module 1 Assignment Rubric to review the Grading Criteria for the Assignment.
  • Click the Module 1 Assignment link. You will also be able to “View Rubric” for grading criteria from this area.
  • Next, from the Attach File area, click on the Browse My Computer button. Find the document you saved as “M1Assgn+last name+first initial.(extension)” and click Open.
  • If applicable: From the Plagiarism Tools area, click the checkbox for I agree to submit my paper(s) to the Global Reference Database.
  • Click on the Submit button to complete your submission.

Grading Criteria

To access your rubric:

Module 1 Assignment Rubric

Check Your Assignment Draft for Authenticity

To check your Assignment draft for authenticity:

Submit your Module 1 Assignment draft and review the originality report.

Submit Your Assignment by Day 7 of Week 2

To participate in this Assignment:

Module 1 Assignment

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