LAD in the laboratory

The poster must be well structured, coherent, written in good
English. The student must demonstrate full comprehension of the chosen
topic and present the poster in a recommended format. Poster topics will
provide a basis for students to demonstrate particularly their achievements in
learning outcomes one to four listed above. The poster should also
demonstrate the integration of information from a wide range of appropriate
reference sources, the text should be concise, charts and illustrations clear,
and the poster attractive visually.
• See next page for list of possible titles
• You can also choose your own topic but check with module leader if
relevance to the field of medical immunology is in doubt
• Please choose a topic from the list as an ‘area guide.’ It is much easier to
prepare a poster on a narrow topic than on a wide one. If you try to prepare a
poster on a huge topic you will be faced with the problem of what to leave out!
So choose a topic within the area guide. For instance, consider the first title on
complement deficiencies and their detection. You could choose ‘Complement
C3 deficiency – including (briefly) its normal roles, immunobiology of the
deficiency including congenital and acquired deficiencies, symptoms and the
detection of C3 deficiency. You could do both a. The second topic is
‘Phagocyte dysfunction and their detection.’ Here, you could choose one 8 | P a g e

disease such as ‘Leukocyte adhesion deficiency’ and include the brief roles of
the ‘healthy cell’, immunobiology of the deficiency, symptoms and then
detection of LAD in the laboratory.
Suggested poster topics

1. Complement deficiencies (narrow choice) and their detection
2. Phagocyte dysfunction and their detection (narrow choice)
3. B cell deficiencies (narrow choice)
4. Immunodeficiency and leukaemia
5. Adenosine deaminase and gene therapy
6. Roles of tumour necrosis factor or Interleukin 1 (one only)
7. Immunology of fever
8. Inflammation (Inflammatory bowel disease / Crohn’s)
9. Endothelial adhesion molecules
10. MHC and disease
11. Stress and immunity
12. Toxic Shock syndrome
13. Roles of IL17 and IL23 in inflammatory responses
14. How HIV destroys cells of the immune system (not life cycle)
15. Biology of the mast cell
16. The immunopathology of asthma / eczema
17. How Th1 / Th2 type responses affect susceptibility to allergies
18. Drug or peanut hypersensitivity (one only)
19. Immunotherapy of allergies
18. Down regulation of the immune response by parasites
19. Interferons and the immune system (alpha, beta or gamma) one only
20. Mutation of CCR5 and HIV infections
21. Perforins and granzymes
22. Clinical application of ‘humanised’ monoclonal antibodies
23 How natural killer cells recognise target cells
24 Plasmaphoresis
25. Chimaeric antibodies
26. Immunopathology of Ankylosing spondylitis
27. Immunopathology of IDDM
28. Immunopathology of SLE and related diseases (scleroderma)
29. Immunopathology of Grave’s disease
30. Immunopathology of Hashimoto’s thyroiditis
31. Immunopathology of Multiple sclerosis
32. Immunopathology of Myasthenia Gravis
33. Rheumatoid factor: pathology and detection
34. The use of oral tolerance in autoimmune diseases
35. Can herbal medicines stimulate the immune system?
36. How Schistosoma avoids the immune response

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